Disclosed is a pharmaceutical or beverage/food which can inhibit the production of an adipocytokine, particularly an adipocytokine that can induce the resistance to insulin, to thereby prevent or ameliorate the occurrence of a morbid condition relating to insulin resistance. The pharmaceutical or beverage/food comprises, as an active ingredient, a compound having a cyclolanostane skeleton, or an extract of a plant belonging to the family Liliaceae or Poaceae with an organic solvent or hot water or a fractionated product of the extract which contains the compound.