Solid forms of N-(4-(7-azabicyclo[2.2,1]heptan-7-yl)-2-trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide

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专利权人:

Vertex Pharmaceuticals Incorporated

发明人:

Beili Zhang,Mariusz Krawiec,Brian Luisi,Ales Medek

申请号：

US13751656

公开号：

US08741922B2

申请日:

2013.01.28

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention relates to substantially crystalline and solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide (Form A-HCl, Form B, Form B-HCl, or any combination of these forms), pharmaceutical compositions thereof, and methods of treatment therewith.

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