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Methods of treating TTP with immunoglobulin single variable domains and uses thereof.
专利权人:
ABLYNX N.V.
发明人:
CHRISTIAN DUBY
申请号:
NL2013007
公开号:
NL2013007B1
申请日:
2014.06.16
申请国别(地区):
NL
年份:
2016
代理人:
摘要:
The present invention is based on the finding that administration of polypeptides comprising at least one Immunoglobulin single variable domains against vWF to human TTP patients provides a significant decrease in the time to response. The invention provides a polypeptide comprising at least one immunoglobulin single variable domain (ISVD) against von Willebrand Factor (vWF) for use in treating a vWF -related disease in a human in need thereof. The invention further relates to dosage unit forms, kits and medical uses for treating TTP.
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