Michael W. Burnet,Jan-Hinrich Guse,Christiane Bauerlein,Ulrike Hahn
申请号:
US15483617
公开号:
US20170313661A1
申请日:
2017.04.10
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A method of treating cancer in which a compound that inhibits the expression, production or release of IL-10 by immune cells is combined with a compound that stimulates the production of IL-12 when given in combination with, or in the presence of TNFa. Said method is effective when provided in addition to standard therapies, notably chemotherapy using cytotoxic drugs and other forms of immune therapy including therapeutic vaccines.