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New gamma crystalline form of ivabradine hydrochloride having specific X-ray diffraction profile
专利权人:
Les Laboratoires Servier
发明人:
Horvath, Stéphane,Auguste, Marie-Noelle,Damen, Gérard
申请号:
NO20060948
公开号:
NO338481B1
申请日:
2006.02.27
申请国别(地区):
NO
年份:
2016
代理人:
摘要:
Gamma crystalline form of ivabradine hydrochloride (I) having specific X-ray diffraction profile of: line position (Bragg angle 2 theta, expressed in degrees) of 4.2-29.1; altitude of line (expressed in blows) of 74-2691; surface of line (expressed in blowsxdegrees) of 15-400; width of the lines with mid-height (expressed in degrees) of 0.0836-0.8029; and inter-reticular distance (expressed in Å) of 3.066-20.762 is new. Gamma crystalline form of ivabradine hydrochloride of formula (I) having specific X-ray diffraction profile of: line position (Bragg angle 2 theta, expressed in degrees) of 4.2-29.1; altitude of line (expressed in blows) of 74-2691; surface of line (expressed in blowsxdegrees) of 15-400; width of the lines with mid-height (expressed in degrees) of 0.0836-0.8029; and inter-reticular distance (expressed in Å) of 3.066-20.762 is new. [Image] ACTIVITY : Antiarrhythmic; Cardiant; Antianginal. MECHANISM OF ACTION : None given.
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