KIM, SEUNG KYUN,金昇均,金昇均,SUNG, YUN JIN,成仑真,成侖真,LEE, BONG SANG,李凤相,李鳳相,JEON, HONG RYEOL,全泓烈,全泓烈
申请号:
TW107105604
公开号:
TW201834643A
申请日:
2018.02.14
申请国别(地区):
TW
年份:
2018
代理人:
摘要:
The present disclosure provides a pharmaceutical formulation, containing: (a) a sustained release part containing itopride or a pharmaceutically acceptable salt thereof, a sustained release polymer, a CO2source, an organic acid and a pharmaceutically acceptable filler and (b) an immediate release part containing itopride or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable filler. The present disclosure may improve medication compliance through once-daily administration.本揭示案提供一種藥物製劑,此藥物製劑包含:(a)緩釋部分,包含依托必利或其醫藥學上可接受之鹽、緩釋聚合物、CO2源、有機酸及醫藥學上可接受之填充劑;以及(b)速釋部分,包含依托必利或其醫藥學上可接受之鹽及醫藥學上可接受之填充劑。本揭示案可經由每日一次投藥來改善藥物順應性。