The invention relates to medical device systems that include a delivery instrument comprising a sheath having an abluminal surface and a luminal surface a radially-expandable frame disposed at least partially within the sheath, the frame having an abluminal surface at least partially in contact with the luminal surface of the sheath, and a luminal surface defining a sub-stantially cylindrical lumen and a fine powder coating disposed on at least one of the abluminal surface of the frame and the luminal surface of the sheath. The invention also relates to methods of manufacturing, loading, and delivering the coated medical devices.
