UTILISATION D'ACIDES BILIAIRES ET DE SELS BILIAIRES COMME AGENTS ANTIBACTÉRIENS POUR L'INHIBITION DE CONJUGAISON BACTÉRIENNE ET DE TRANSFERT DE GÈNE HORIZONTAL
Tel HaShomer Medical Research Infrastructure and Services Ltd.
发明人:
GAL-MOR, Ohad,RAHAV, Galia
申请号：
EP17759380
公开号：
EP3423099A4
申请日:
2017.02.28
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Methods of inhibiting bacterial conjugation, bacterial horizontal gene transfer or bacterial growth are disclosed. The methods comprise contacting bacteria with an effective amount of a bile acid or a bile salt, wherein the effective amount does not affect viability of the bacteria. A method of increasing susceptibility of bacteria to antibiotic treatment is also disclosed as well as methods of decontaminating a farm animal housing or a medical surface and methods of treating water. Also disclosed are compositions effective in inhibiting bacterial conjugation, bacterial horizontal gene transfer and bacterial growth.
