The Trustees of the University of Pennsylvania;Inovio Pharmaceuticals, Inc.;The Wistar Institute of Anatomy and Biology
发明人:
Weiner, David B.,Patel, Ami,Yan, Jian
申请号：
AU2017261306
公开号：
AU2017261306A1
申请日:
2017.05.05
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
Nucleic acid molecules and compositions comprising one or more nucleic acid sequences that encode a consensus Ebolavirus glycoproteinimmunogens are disclosed. The coding sequences optionally include operable linked coding sequence that encode a signal peptide. Immunomodulatory methods and methods of inducing an immune response against Ebolavirus are disclosed. Method of preventing Ebolavirus and methods of treating individuals infected with Ebolavirus are disclosed. Consensus Ebolavirus proteins are disclosed.
