BCMA-based stratification and therapy for multiplemyeloma patients

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专利权人:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人:

HEBEIS JASMIN BARBARA,BORGES ERIC

申请号：

AP2013007178

公开号：

AP2013007178A0

申请日:

2012.04.20

申请国别(地区):

AP

年份:

2013

代理人:

摘要：

The present invention relates to methods for the stratification of a multiple myeloma (MM) patient comprising determining whether or not B-cells, preferably malignant B-cells of said patient express BCMA protein on their surface. Also, methods for selecting an antibody-based multiple myeloma (MM) therapy is based on whether or not BCMA is expressed on the cell surface of B-cells, preferably malignant B-cells of a patient. Furthermore, antibody-based therapies for patients who have BCMA positive malignant B-cells are provided.

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