The present invention relates to the field of pharmaceutical formulation techniques. The invention provides a low dosage pharmaceutical composition for transdermal delivery of hormones, preferably a progestin, such as a Gestodene, and an estrogen, preferably Ethinylestradiol so as to achieve plasma concentration profiles effective in inhibiting ovulation in a woman.本發明係關於醫藥調配物技術領域。本發明提供一種低劑量醫藥組合物,用於經皮遞送激素,較佳為孕酮(如孕二烯酮),及雌激素(較佳為乙炔雌二醇),以達到有效抑制女性排卵之血漿濃度概況。