The present invention provides a multi-coating-structure type nano silver liposome, which is a nano silver liposome composed of a first core part and a surface layer part, wherein the first core part contains, in the interior thereof, a plurality of first silver particles and at least a first silver carrying liposome particle. The plurality of first silver particles is at least one selected from nano silver and a composite of nano silver grafted with nano gold, enclosing or surrounding the exterior of the first silver carrying liposome. The first silver carrying liposome particle contains, in the exterior thereof, one or a plurality of second silver particles, and the first silver carrying liposome particle is at least one selected from liposome, phytosome, ethosome, phosphatidylcholine, phosphatidylserine, and phosphatidylinositol, and a mixture thereof.本發明提供一種多重包覆結構型奈米銀微脂體,其係由包括第一核心部及表層部所構成之奈米銀微脂體,其中該第一核心部之內部係容納有複數個第一銀粒子、及至少一個第一載銀微脂顆粒;該複數個第一銀粒子係由奈米銀、及奈米銀嫁接奈米金複合體中所選出之至少一種、且包覆或環繞於該第一載銀微脂顆粒的外部;該第一載銀微脂顆粒之內部係容納有一個或多個第二銀粒子;該第一載銀微脂顆粒係從脂質微脂體、磷脂質微脂體、乙醇微脂體、磷脂醯膽鹼、磷脂質絲胺酸、磷脂酸肌醇、及彼等之混合物中所選出之至少一種。10、20、30‧‧‧奈米銀微脂體110‧‧‧第一核心部111‧‧‧第一銀粒子112‧‧‧第一載銀微脂顆粒120‧‧‧第一表層部