National University Corporation Kumamoto University
发明人:
Takumi ERA,Takayuki Kiboku
申请号：
US15776152
公开号：
US20200253942A1
申请日:
2016.11.17
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A pathological mechanism in FOP patients is further revealed, and development of a novel therapeutic drug, therapeutic method, diagnostic method, etc. utilizing an obtained finding is provided. The inventors have found a novel finding that in FOP, ectopic ossification, which occurs by an inflammation due to an injury, etc., is mediated by PAR1 to occur. From this finding, the inventors completed the present invention relating to a drug, etc. characterized by suppressing ectopic ossification in FOP by inhibiting PAR1.
