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Tricyclic pyrrolopyridine compound and JAK inhibitor
专利权人:
日産化学工業株式会社
发明人:
▲高▼橋 啓治,渡辺 恒夫,林 圭史,栗原 一典,中村 隆典,山本 明生,西村 拓也,神山 利彦,日高 夕貴
申请号:
JP2014560789
公开号:
JP6248948B2
申请日:
2014.02.05
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
To provide a novel tricyclic pyrrolopyridine compound having a JAK inhibitory activity and useful for prevention, treatment and/or improvement of particularly autoimmune diseases, inflammatory diseases and allergic diseases. A novel tricyclic pyrrolopyridine compound represented by the formula (I), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof: wherein the respective substituents are defined in detail in the specification, and R 1 is a C 1-6 alkyl group or the like, R 2 is a hydrogen atom or the like, R 3 is a hydrogen atom or the like, the ring A is C 3-11 cycloalkane or the like, L 1 is a C 1-6 alkylene group or the like, and R 4 is NR a R b or the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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