Method for producing a medicinal product comprising a biologically active protein, medicinal product, and the product in the form of a body freeze-dried

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专利权人:

INTERVET INTERNATIONAL B.V.

发明人:

Kevin O'Connell,Sandhya Buchanan,Kevin OConnell

申请号：

BR112015000404

公开号：

BR112015000404A2

申请日:

2013.07.09

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

1 / 1 Summary u00e2 u20ac u0153m u00e3 u2030todo to produce a medicinal product comprising a biologically active prote u00e3 ufffdna, medicinal product, and the product in the form of a body liofilizado u00e2 u20ac ufffd this inven u00e3 u00a7 u00e3 u00a3o refers to a m u00e3todo to produce a medicinal product comprising a prote u00e3 u00adna biologically active comprising the steps of providing a composi u00e3 u00a7 u00e3 u00a3o comprising an aqueous solvent.The prote u00e3 u00adna biologically active and 20% by weight and 60% by weight of a a u00e3 u00a7 u00e3 u00bacar n u00e3 u00a3o polim u00e3rico, freeze the composi u00e3 u00a7 u00e3 u00a3o, thus forming at least a frozen body comprising the solvent to form frozen by placing the frozen body in a drying apparatus while being car Watered by a support.The support comprising one or more elements of restri u00e3 u00a7 u00e3 u00a3o that define one or more contours of the support, in that, in the m u00e3ximo, 30% of the superf u00e3 u00adcie body est u00e3 u00a3o cont u00e3 u00adguos with one or more elements of restri u00e3 u00a7 u00e3 u00a3o, reduce a press u00e3 u00a3o in drying apparatus below the press u00e3 u00a3o at Mosf u00e3rica, provide heat to the body to sublimate the solvent frozen body and obtain a body dry.The inven u00e3 u00a7 u00e3 u00a3o tamb u00e3m refers to a product obten u00e3 u00advel that m u00e3todo.1 / 1 resumo “mã‰todo para produzir um produto medicinal compreendendo uma proteã�na biologicamente ativa, produto medicinal, e, produto na forma de um corpo liofilizadoâ€� a presente invenã§ã£o refere-se a um mã©todo para produzir um produto medicinal compreendendo uma proteã­na biologicamente ativa compreendendo as etapas de fornecer uma composiã§ã£o aquosa compreendendo um solvente, a proteã­na biologicamente ativa e entre 20% em peso e 60% em peso de um aã§ãºcar nã£o polimã©rico, congelar a composiã§ã£o, assim formando pelo menos um corpo congelado compreendendo o solvente em forma congela

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中国工程科技知识中心

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http://www.ckcest.cn/home/