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BIODEGRADABLE OCULAR IMPLANTS WITH LONG-TERM RELEASE CHARACTERISTICS
专利权人:
发明人:
申请号:
EP05735919.2
公开号:
EP1740153B1
申请日:
2005.04.14
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention provides a bioerodible implant for treating an ocular condition, the implant comprising (a) a dispersion comprising an active agent dispersed with a first bioerodible polymer, and (b) a particle comprising the active agent and a second bioerodible polymer, wherein the particle has an active agent release characteristic which differs from the active agent release characteristic of the dispersion (continued release period of 50d to 1y). In addition, the invention provides a bioerodible implant for treating a posterior ocular condition, the bioerodible implant comprising (a) a first region containing a first mixture of an active agent and a first bioerodible polymer, and (b) a second region containing a second mixture of the active agent and a second bioerodible polymer, wherein the first and second regions have different active agent release characteristics. Corresponding methods for producing bioerodible implants are also provided.
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