Andrea Bauer,Nandkumar Nivritti Bhogle,Xiaoxia Chen,Shahla Jamzad,Robert Joseph Prytko,Kostas Saranteas,Harold Scott Wilkinson,Haitao Zhang
申请号:
US16277443
公开号:
US20190256525A1
申请日:
2019.02.15
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided are salts of (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine and various of crystal forms thereof, and compositions, medicaments, pharmaceutically acceptable formulations thereof, and methods of making same. In addition, provided are compounds comprising specific particle size distributions of crystalline (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine HCl and methods of making and modulating the particle size distributions.