Oxalate Salts of Teneligliptin Salts and Solvates thereof, Intermediates, Process of Prepration and Markers thereof农业专利-农业学术服务平台

发明人:: KADAM, SURESH MAHADEV,可当苏瑞旭玛哈德夫,可當蘇瑞旭瑪哈德夫,KANSAGRA, BIPIN PARSOTTAM,肯沙葛拉比平帕索谭,肯沙葛拉比平帕索譚,KALE, SHRIKRISHNA KANTILAL,卡尔史瑞克里许纳肯提拉,卡爾史瑞克里許納肯提拉,BHIRUD, SHEKHAR BHASKAR,比若德许卡尔巴斯卡尔,比若德許卡爾巴斯卡爾

摘要：: The present invention provides oxalate salts of teneligliptin and solvates thereof exhibiting superior physiochemical properties. In particular, crystalline form of teneligliptin 2.5 oxalate 1.0 hydrate and crystalline form of teneligliptin 3.0 oxalate 1.0 hydrate are disclosed. Also provided are methods of preparing the same, and uses thereof.本發明提供具有優越的生物化學性質的特力利汀草酸鹽與其溶劑合物。尤其是,本發明揭露了特力利汀鹽2.5草酸鹽1.0水合物的結晶形式,及特力利汀鹽3草酸鹽1.0水合物的結晶形式。本發明同時提供其製備方法及其用途。