PROBLEM TO BE SOLVED: To provide a method of manufacturing a device introduced into a subject which has high water-tightness in an internal space.SOLUTION: A method of manufacturing a device introduced into a subject in which an outer periphery is covered with a first housing and a second housing that are joined to each other, and which can be introduced into a subject includes: a space part forming step for forming a space part in a first joining part of the first housing or a second joining part of the second housing that are overlapped with each other in joining; and a joining step in which an adhesive is applied to the first joining part or the second joining part, and the first joining part and the second joining part are fitted together to overlap with each other for discharging gas in a space covered with the first housing and the second housing from the space part and for joining the first housing and the second housing by sealing the space part by the adhesive.SELECTED DRAWING: Figure 1【課題】内部空間の水密性が高い被検体内導入装置を製造することができる被検体内導入装置の製造方法を提供すること。【解決手段】被検体内導入装置の製造方法は、接合された第1の筐体と第2の筐体とにより外周が覆われており、被検体内に導入可能な被検体内導入装置の製造方法であって、接合時に互いに重なり合う前記第1の筐体の第1の接合部又は前記第2の筐体の第2の接合部に空間部を形成する空間部形成工程と、前記第1の接合部又は前記第2の接合部に接着剤を塗布し、前記第1の接合部と前記第2の接合部とが重なり合うように嵌め合わせることによって、前記第1の筐体及び前記第2の筐体に覆われた空間内にある気体が前記空間部から排出され、かつ、前記空間部を前記接着剤で封止して、前記第1の筐体と前記第2の筐体とを接合する接合工程と、を含む。【選択図】図1