The present invention relates to a gastric retention active delivery system in the form of a coated capsule, which, in contrast to prior art delivery systems exhibiting relatively poor floating-properties, and thus requiring size expansion capability in order to securely delay passage through the pylorus, reliably stay afloat for several hours. This is achieved by combining pore forming components and flexible polymer components in the coating in suitable proportions. The present invention, further, relates to the use of gastric retention active delivery systems of the invention for the delivery of one or more water soluble active components A to a mammal.
