The Board of Regents of The University of Texas System
发明人:
MORRISON, Sean,YUE, Rui
申请号:
EP16783640
公开号:
EP3285792A4
申请日:
2016.04.18
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present disclosure describes the C-type lectin CLEC11a as a bone growth factor. Clec11a-deficient mice showed reduced bone volume and mineralization, while bone resorption remained unchanged. Administration of recombinant Clec11a systemically promoted bone formation in mice at risk for osteoporosis.