Combination of AS1411 and SAPC-DOPS for the Treatment of Glioblastoma Multiforme

• 收藏
• 分享

专利权人:

University of Cincinnati

发明人:

Xiaoyang Qi,Nikhil Shukla

申请号：

US16756247

公开号：

US20200237866A1

申请日:

2018.10.15

申请国别(地区):

US

年份:

2020

代理人:

摘要：

A method of inducing cell death in a glioblastoma multiforme cancer cell is provided, the method comprising administering to the cell a combination of therapeutic agents comprising: saposin C and dioleoylphosphatidylserine (SapC-DOPS), and nucleolin aptamer AS1411, wherein cell death of the cancer cell is induced. Also provided are methods of treating glioblastoma multiforme, methods of inhibiting growth of a glioblastoma multiforme tumor, kits, and pharmaceutical compositions comprising SapC-DOPS and

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/