BAURIN NICOLAS,BERNE PIERRE-FRANCOIS,BLANCHE FRANCIS,BONO FRANCOISE,CAMERON BEATRICE,DABDOUBI TARIK,HERBERT CORENTIN,MIKOL VINCENT,REMY ELISABETH
申请号：
NZ60290509
公开号：
NZ602905A
申请日:
2009.07.07
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
602905 Disclosed is the use of a FGF-R4 antagonist antibody which comprises CDRs of sequence SEQ ID Nos. 9 (TSGMGVS), 10 (HIYWDDDKRYNPSLKS), 11 (DYYASSFDY), 12 (RASQSISNYLH), 13 (YASQSIS) and 14 (QQSNSWPFT), where each one of the CDRs may differ by one or two amino acids compared with its respective sequence mentioned above, provided that the antibody keeps its binding specificity for FGF-R4, in the manufacture of a medicament to treata disease related to a pathological angiogenesis.
