COSMETIC AND PHARMACEUTICAL TREATMENT PROCESS FOR REDUCING BOTH WRINKLES AND INCREASING FERMINE WITHOUT LIPOLYSIS AND COMPOSITIONS FOR IMPLEMENTING THE SAME
Combination (I) comprises at least one sirtuin inhibitor with at least one xanthic base ACTIVITY : Dermatological; Muscular-Gen. MECHANISM OF ACTION : Sirtuin (SIRT) inhibitor. The ability of (I) to inhibit the endogenous synthesis of sirtuin 1 was tested in epidermal cells (keratinocytes). The result showed that the extract of native extract of baobab fruit and an extract of Hibiscuscalyces (50/50) at a concentration of 0.008% (a few thousandths of a percent) reduced the expression of a SIRT-1 of epidermal cells (keratinocytes) to 55%.