ARTIFICIAL DNA SEQUENCE WITH OPTIMIZED LEADER FUNCTION IN 5' (5'-UTR) FOR THE IMPROVED EXPRESSION OF HETEROLOGOUS PROTEINS IN PLANTS

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专利权人:

UNIVERSITA DEGLI STUDI DI UDINE;UNIVERSITA' DEGLI STUDI DI UDINE

发明人:

MARCHETTI, STEFANO,DE AMICIS, FRANCESCA,PATTI, TAMARA

申请号：

NZ57851807

公开号：

NZ578518A

申请日:

2007.12.27

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is an Artificial DNA sequence of a 5'-UTR leader region (containing one or more copies of the octamer ACAATTAC) effective in enhancing the expression of heterologous proteins in plants, and having elements favourable to gene expression in plants, comprising at least a poly(CAA) region, meaning an oligonucleotide consisting of two or more copies of the CAA element contiguous with each other in combination with at least a poly(CT) region, meaning an oligonucleotide consisting of two or more copies of the CT element contiguous with each other. Further disclosed are bacterial strains and engineered virus strains containing said sequence, and plant cells and plants transformed with expression vectors containing said sequence.

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