4-dimethylaminobutyric acid derived compounds, process for their preparation, pharmaceutical compositions comprising them, method for the therapeutic or prophylactic treatment of diseases that are modulated by cpt2 inhibitors and use of these compounds
GERALD LEWIS KAPLAN,JEFFERSON WRIGHT TILLEY,MIRJANA ANDJELKOVIC,ODILE CHOMIENNE,PATRIZIO MATTEI,SIMONA M. CECCARELLI
申请号：
BRPI0911159
公开号：
BRPI0911159A2
申请日:
2009.04.20
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
This invention relates to novel 4-dimethylaminobutyric acid derivatives of the formula wherein A1, A2, R1, m and n are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds inhibit carnitine palmitoyl transferase (CPT) activity, in particular CPT2 activity, and can be used as medicaments in methods for the treatment of diseases modulated by CPT2 inhibitors.
