EFFETS THÉRAPEUTIQUES DES BRYOSTATINES, DE LEURS ANALOGUES, ET D'AUTRES SUBSTANCES CONNEXES SUR L'AFFAIBLISSEMENT DE LA MÉMOIRE INDUITE PAR UN TRAUMATISME CRÂNIEN ET SUR LES LÉSIONS CÉRÉBRALES
The invention provides for the use of protein kinase activators or boosters of nerve growth factor (NGF), brainderived neurotrophic factor (BDNF) or other neurotrophic factors to treat head trauma. Specifically, the present invention provides methods of treating head trauma comprising the steps of identifying a subject having suffered a head trauma and administering to said subject an amount of a pharmaceutical composition comprising a protein kinase C (PKC) activator or 4-methylcatechol acetic acid (MCBA) and a pharmaceutically acceptable carrier effective to treat at least one symptom of head trauma.
