COMPOSÉ D'ACIDE HYDROXAMIQUE CONTENANT DE LA QUINOLYLE ET PROCÉDÉ DE PRÉPARATION ASSOCIÉ, ET COMPOSITION PHARMACEUTIQUE CONTENANT CE COMPOSÉ ET UTILISATION ASSOCIÉE
Beijing Konruns Pharmaceutical Co., Ltd.;Guangzhou ESA Biotech Co., Ltd.
发明人:
申请号:
EP11872645.4
公开号:
EP2769976B1
申请日:
2011.09.27
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Provided in the present invention is a quinolyl-containing hydroxamic acid compound as shown in formula (I), at the same time also disclosed is the preparation method of the compound and the use thereof, and a pharmaceutical composition containing the quinolyl-containing hydroxamic acid compound. Such compounds are inhibitors of protein kinases and/or histone deacetylases, and can be used in the treatment of diseases caused by the abnormal activity of protein kinases and/or histone deacetylases, for example, tumors, etc.