Vector comprising Ehrlichia canis sequence as well as transgenic microoganism

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专利权人:

发明人:

DAVID H. WALKER,XU-JIE YU

申请号：

BR9913652

公开号：

BR9913652B1

申请日:

1999.08.27

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

The present invention provides a 120-kDa protein gene of Ehrlichia canis, amplified by PCR using primers derived from the DNA sequences flanking the Ehrlichia chaffeensis 120-kDa protein gene. The recombinant E. canis 120-kDa protein contains 14 tandem repeat units with 36 amino acids each. The repeat units are hydrophilic and predicted to be surface-exposed. Also disclosed is that the recombinant E. canis 120-kDa protein is antigenic and reacts with sera from dogs convalescent from canine ehrlichiosis.

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