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METHODS FOR TREATING CANCER
专利权人:
UCL BUSINESS LTD
发明人:
VON KARSTEDT, Silvia,WALCZAK, Henning
申请号:
DK14741936
公开号:
DK3016682T3
申请日:
2014.07.03
申请国别(地区):
DK
年份:
2020
代理人:
摘要:
The present invention relates to methods and materials for treating an individual with KRAS-mutated cancer or a cancer in which ROCK is inhibited independently of mutated KRAS. The invention is based on the prevention or disruption of the binding of TRAIL-Receptor to its ligand, TRAIL, in vivo, for example by use of an agent that neutralizes TRAIL and/or a the TRAIL-Receptor (such TRAIL-R2) and/or diminishes TRAIL/TRAIL-Receptor activity, thereby reducing cancer cell transformation, migration and metastasis, prolonging survival of patients.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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