Paul Ponath,Patricia Rao,Michael Rosenzweig,L. Mary Smith,Jose F. Ponte
申请号：
US11471397
公开号：
US08901281B2
申请日:
2006.06.19
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides binding molecules that specifically bind to ILT3, e.g., human ILT3 (hILT3), on antigen presenting cells, such as for example, monocytes, macrophages and dendritic cells (DC), e.g., monocyte-derived dendritic cells (MDDC). Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof. Methods of using the binding molecules of the invention to detect human ILT3 or to modulate human ILT3 activity, either in vitro or in vivo, are also encompassed by the invention.
