CHOI, YOUNG KWEN,최영권,KIM, JUNG JU,김정주,LEE, JUNG SIK,이정식,KIM, SUNG SOO,김성수
申请号:
KR1020110022958
公开号:
KR1020120107153A
申请日:
2011.03.15
申请国别(地区):
KR
年份:
2012
代理人:
摘要:
PURPOSE: A fentanyl transdermal patch is provided to make the contact of a medicine/viscosity layer with skin close while constantly maintaining the skin transmittance of fentanyl for three days. CONSTITUTION: A fentanyl transdermal patch includes a supporter and a medicine/viscosity layer. The supporter is placed on a side of the medicine/viscosity layer. The medicine/viscosity layer includes 60 to 80 parts by weight of acrylic-rubber hybrid polymer and 5 to 20 parts by weight of one or more selected from a group composed of fentanyl, fentanyl derivatives, and pharmaceutical salt thereof. [Reference numerals] (AA) Medicine protecting layer; (BB) Medicine-contained adhesive layer; (CC) Thin film layer아크릴-고무 하이브리드를 약물·점착층으로 포함하는 펜타닐 경피 패치제로, 펜타닐의 피부투과도가 일정하게 3일간 유지되면서 피부와의 접촉을 긴밀하게 하여 수분이나 땀의 방출로 인한 피부탈착이 개선되고 피부 자극이 개선된 펜타닐 경피 패치제가 제공된다.