The present invention relates to methods and systems for bi-planar fluoroscopy, such as with dual fluoroscopes mounted to C-arms for lateral and anterior-posterior (AP) fluoroscopy of a patient. In one aspect of the invention, a bi-planar fluoroscopy system may generally include first and second fluoroscopes. In general, each fluoroscope may be positioned and aimed to provide different viewing angles and/or orientations of the target, such as, for example, placement for lateral and AP views of the target. In some exemplary embodiments, both fluoroscopes may be maintained as “fixed or locked” in AP and lateral positions, respectively, for example, and then each controlled by a set of proximally located control mechanisms, such as one control mechanism (e.g. a foot pedal or voice command specific to operation of a given fluoroscope each). The control mechanisms may further be adapted for use by a single operator individually and/or simultaneously. This may be particularly desirable for spinal procedures, such as for pedicle screw or kyphoplasty balloon placement, and may provide significantly enhanced efficiency and time reduction for these procedures, by completely negating subsequent movements after initial AP and lateral positions have been fixed with C-arms locked into such positions.