The present invention relates to a system for the central control of devices used during an operation, comprising a first control unit for control of said devices. The system is characterized in that a second control unit is provided which is connected to the first control unit for exchange of information. The first control unit may be embodied as closed system for control of at least those devices which carry out safety-related functions (safety-related devices), and the second control unit may be embodied as open system for control of the remaining devices which carry out non safety-related functions (non safety-related devices). The invention further relates to a method for the central control of devices.