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皮膚残留薬剤計測装置及び皮膚残留薬剤計測方法
专利权人:
KEIO GIJUKU
发明人:
ARAI TSUNENORI,荒井 恒憲,OGAWA EMIYU,小川 恵美悠
申请号:
JP2016204615
公开号:
JP2018064720A
申请日:
2016.10.18
申请国别(地区):
JP
年份:
2018
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide a measuring device for a drug remaining in the skin and a measuring method for a drug remaining in the skin capable of easily and reliably examining photodermatosis, which is an adverse effect of a treatment using a photosensitizing reaction, in a non-invasive manner with excellent reproducibility.SOLUTION: A measuring device S for a drug remaining in the skin for measuring an amount of a photosensitive substance remaining in a skin tissue of a living body includes a cuff 10 wound around a part to be measured of the living body, which oppresses the part to be measured. The cuff 10 is provided with irradiation means 23 for irradiating a skin tissue of the part to be measured, with an excitation light, and detection means 24 and 32 for detecting the intensity of a fluorescent light discharged in the skin tissue in response to the irradiation of the excitation light. Estimated residual drug amount calculation means 51 is provided for calculating an estimated amount of the photosensitive substance remaining in the skin tissue using the value of the intensity of the fluorescent light detected by the detection means 24 and 32.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2018,JPO&INPIT【課題】光増感反応を用いた治療の副作用である光線過敏症を、非侵襲的な方法で、簡易に、信頼性,再現性良く検査することが可能な皮膚残留薬剤計測装置及び皮膚残留薬剤計測方法を提供する。【解決手段】生体の皮膚組織に残留した光感受性物質の量を計測する皮膚残留薬剤計測装置Sである。生体の被測定部に巻回されて被測定部を圧迫するためのカフ10を備え、カフ10には、被測定部の皮膚組織に励起光を照射する照射手段23と、励起光の照射に応じて皮膚組織で放出される蛍光の強度を検出する検出手段24,32と、が設けられ、検出手段24,32で検出された蛍光の強度の値を用いて、皮膚組織に残留した光感受性物質の推定量を算出する推定残留薬剤量の算出手段51と、を備える。【選択図】図1
来源网站:
中国工程科技知识中心
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