A high frequency handpiece for skin treatment is provided, which includes: a handle of which one end is connected to a high frequency generator and the other end has an opening formed thereon, in which the handle has a cylindrical shape to allow grip by hand; and a needle cartridge fitted to one side of the handle and including a needle formed thereon to output a high frequency to skin when supplied with power, in which the needle cartridge includes a holder having both open sides and a passage formed therein; a needle assembly coupled to one side of the holder and having the needle formed therein to be inserted into the skin; a connector coupled to an opening on the other side of the holder, connected to one side of the needle assembly, and having a fitting part formed at the other side; and a power plug removably fitted into the fitting part of the connector and is coupled to the handle to supply power. Accordingly, because the cartridge having needles integrally formed thereon can be separated from the handle, replacement with a new cartridge can be facilitated, and the needles can be replaced in a more hygienic manner.