A system and method for assessing Peripheral Nerve Stimulation (PNS). The system receives an imaging pulse sequence to be applied to at least a region of interest (ROI) of a subject arranged in the imaging system, the imaging pulse sequence identifying coil parameters related to at least one coil. The system obtains a first model including a plurality of tissue types and corresponding electromagnetic properties in the ROI. The system then obtains a second model indicating at least one of location, orientation, and physiological properties of one or more nerve tracks in the ROI. The system estimates a plurality of PNS thresholds in the ROI caused by the imaging pulse sequence applied in the imaging system using the first model, the second model, a nerve membrane model, and the coil parameters.
