A spray-type respiratory therapy device has a body and an atomizing device on one side of the body, and a guiding separation member is disposed in the body, and a guiding separation channel is disposed in the guiding separation member, and the guiding separation channel is opposite to the side of the atomizing device An air inlet is formed, and an air outlet is formed on the other side. The atomizing device can use a single or a plurality of atomizing members to atomize the liquid and then pass through the flow guiding separation passage, so that the atomized liquid of the larger particles collides and adheres to the guide. The flow separates the inner wall of the channel, thereby removing the atomized liquid having a large particle size, preventing the atomized liquid of the larger particle from entering the human body, causing the lung to be absorbed, affecting the therapeutic effect, and causing problems such as discomfort or coughing of the user.一種噴霧式呼吸治療器,具有本體以及本體一側之霧化裝置,本體內設置有導流分離件,導流分離件內設置有導流分離通道,導流分離通道正對於霧化裝置側方形成有進氣口,另一側形成有出氣口,霧化裝置可使用單一個或複數霧化件,將液體霧化後通過導流分離通道,使較大顆粒之霧化液體碰撞附著於導流分離通道內壁,進而去除粒徑較大之霧化液體,避免較大顆粒之霧化液體進入人體,造成肺部無法吸收而影響治療功效,以及引起使用者不適或咳嗽等問題。