LIM, CAROL,BRUNO, BENJAMIN J.,MILLER, GEOFFREY D.,DIXON, ANDREW S.
申请号：
CA2944043
公开号：
CA2944043A1
申请日:
2015.03.25
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
In one aspect, the invention relates to peptides comprising the Bcr-Abl coiled-coil oligomerization domain and an alpha helix stabilizing moiety, mutant forms thereof, truncated forms thereof, derivatives thereof, and related peptides, which are useful as inhibitors of the Bcr-Abl chimeric protein； pharmaceutical compositions comprising the compounds； and methods of treating hyperproliferative disorders associated with Bcr-Abl using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
