lipase, use of a lipase or a mixture of lipases, pharmaceutical composition, and method for treating a disease

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专利权人:

NOVOZYMES A / S;SOLVAY PHARMACEUTICALS GMBH

发明人:

ALLAN SVENDSEN,KIM BORCH,PETER COLIN GREGORY

申请号：

BRPI0612274

公开号：

BRPI0612274A2

申请日:

2006.06.16

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

The pharmaceutical use of lipases related to a variant of the Thermomyces lanuginosus (Humicola lanuginosa) lipase comprising amino acids 1-269 of SEQ ID NO: 1, optionally in combination with a protease and/or an amylase. Examples of medical indications are: Treatment of digestive disorders, pancreatic exocrine insufficiency (PEI), pancreatitis, cystic fibrosis, diabetes type I, and/or diabetes type II. The lipases of the invention have an improved efficacy in vivo, are stable against protease-degradation, and/or are stable in the presence of bile salts.

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中国工程科技知识中心

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