Richard John Dansereau,Brian Laster,Erin Swigart,Ashraf Traboulsi
申请号:
US14973759
公开号:
US09855227B2
申请日:
2015.12.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
An oral dosage form to deliver diphenhydramine through the sublingual or buccal mucosa. The oral dosage form can contain diphenhydramine, or a pharmaceutically acceptable salt thereof, a permeability enhancer, and a buffering agent. The buffering agent can achieve a pH of about 7.0 to about 8.0. The diphenhydramine can completely dissolve within about 2 minutes.