Falko Diedrich,Birgit Neudecker,Eberhard Wieland,Joseph A. Lewis, II,Joseph C. DiNardo,Andrew S. Thompson,James Alan Kerschen,Peter C. Wade
申请号：
US13714136
公开号：
US20130101534A1
申请日:
2012.12.13
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to novel carboxylic acid-substituted idebenone derivatives, skin treatment compositions containing these carboxylic acid-substituted derivatives, methods of treating skin changes by topical application of these carboxylic acid-substituted idebenone derivatives, and their methods of synthesis. The carboxylic acid-substituted idebenone derivatives of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the carboxylic acid-substituted idebenone derivatives of the present invention have an antioxidant effect that is useful in treating a skin change.
