Methods of converting a patients treatment regimen from intravenous administration of an opioid to oral co-administration of morphine and oxycodone using a dosing algorithm to provide analgesia
Richards, Patricia T.,Stern, Warren C.,Mengle-Gaw, Laurel J.,Schwartz, Benjamin D.
申请号：
AU2011302137
公开号：
AU2011302137A1
申请日:
2011.09.14
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
A method of converting a treatment for pain comprising intravenous administration of opioids, to a treatment for pain comprising oral administration of a first dose of an immediate release mgrphine-oxycodone combination in patients in need of analgesia. The method may comprise (1) determining a four-hour average oral morphine equivalents, a one-hour average oral morphine equivalents, or determining a net average hourly inlravenous dose, and (2) orally administering to the patient a first dose of a morphine-oxycodone combination in a 3:2 ratio by weight every four to six hours. Also, a method of treating pain in patients who had been administered opioids intravenously, comprising using a dosing algorithm lo determine the first dose of the immediate release morphine-oxycodone combination.
