Robert T. Lyons;Michael R. Robinson;John T. Trogden;Scott M. Whitcup
发明人:
Robert T. Lyons,Michael R. Robinson,John T. Trogden,Scott M. Whitcup
申请号：
US11828561
公开号：
US08846094B2
申请日:
2007.07.26
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Viscous formulations and methods of using such compositions, useful for intramuscular and intra-articular injection are provided to treat peripheral conditions. Such compositions can include triamcinolone particles present in a therapeutically effective amount, a viscosity inducing component, and an aqueous carrier component. The compositions have viscosities of at least about 10 cps or about 100 cps at a shear rate of 0.1/second. In a preferred embodiment, the viscosity is in the range of from about 80,000 cps to about 300,000 cps. In a most preferred embodiment, the viscosity is in the range of from about 140,000 cps to about 280,000 cps at a shear rate of 0.1/second at 25° C. The compositions advantageously suspend the triamcinolone particles for prolonged periods of time.
