The purpose of the present invention is to provide a freeze-dried preparation having improved hepatocyte growth factor storage stability in comparison to conventional freeze-dried preparations. The present invention provides a freeze-dried preparation containing (1) hepatocyte growth factor, (2) trehalose, and (3) one or more compounds selected from the group consisting of arginine, histidine, lysine, meglumine, glutamic acid, aspartic acid, proline, creatine, creatinine, trishydroxymethylaminomethane, and pharmacologically acceptable salts of these.
