Angela Zarling,Victor H. Engelhard,Kara L. Cummings,Rebecca C. Obeng
申请号:
US15303677
公开号:
US20170029484A1
申请日:
2015.04.15
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided are isolated TCRs, TCR-like molecules, and portions thereof that bind to phosphopeptide-HLA-A2 complexes. The isolated TCRs, TCR-like molecules, or portions are optionally soluble TCRs, TCR-like molecules, or portions. Also provided are isolated nucleic acids encoding the disclosed TCRs, TCR-like molecules, or portions; host cells that contain the disclosed TCRs, TCR-like molecules, or portions; pharmaceutical compositions that include the disclosed TCRs, TCR-like molecules, portions, nucleic acids, and/or T cells; kits; and methods of using the same.