Nathalie Demotte,Pierre Van Der Bruggen,Thierry Boon-Falleur
申请号:
US13429873
公开号:
US08951747B2
申请日:
2012.03.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to methods and compositions which modulate T lymphocyte activity. It has been found that two, T lymphocyte receptors, especially TCR and CD8, are present at a distance from each other on T lymphocyte surfaces. Via use of modulators which change the distance between these receptors, the activity of the T lymphocyte is modulated.