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AGOMELATINE HYDROCHLORIDE HYDRATE AND PREPARATION THEREOF
专利权人:
LES LABORATOIRES SERVIER
发明人:
SHAN, HANBIN,YUAN, ZHEDONG,ZHU, XUEYAN,ZHANG, PENG,PAN, HONGJUAN,YU, XIONG
申请号:
SG2012065009
公开号:
SG183868A1
申请日:
2011.03.17
申请国别(地区):
SG
年份:
2012
代理人:
摘要:
An agomelatine hydrochloride hydrate of formula (I), preparation, use, and pharmaceutical composition thereof are provided. Said hydrate obtained through the present method has significant increased solubi1ity than agomelatine, and therefore is more suitable for manufacturing pharmaceutical formulations. Using the present method, high purity can be obtained through a simple process, free of any complicated steps. Wherein X is Cl.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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