靶向HER2的雙特異性抗原結合構建體

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专利权人:

发明人:

申请号：

HK17102693.7

公开号：

HK1228932A

申请日:

2017.03.16

申请国别(地区):

HK

年份:

2017

代理人:

摘要：

Provided herein are biparatopic antigen-binding constructs that specifically bind HER2. The biparatopic antigen-binding constructs comprise one antigen-binding moiety that binds to ECD2 of HER2, a second antigen-binding moiety that binds to ECD4 of HER2, and an Fc. At least one of the antigen-binding moieties is an scFv. The biparatopic antigen-binding constructs can be used in the treatment of cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/