Arbetman, Alejandra Elena,Colosi, Peter,Lochrie, Michael A.,Surosky, Richard T.
申请号:
DK11158742
公开号:
DK2357189T3
申请日:
2004.06.21
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
Methods of making and using recombinant AAV virions with decreased immunoreactivity are described. The recombinant AAV virions include mutated capsid proteins or are derived from non-primate mammalian AAV serotypes and isolates that display decreased immunoreactivity relative to AAV-2.